England is set to become the first country in the world to introduce a national gonorrhoea vaccination programme, in a move hailed by health officials as a “landmark moment for sexual health”. The rollout will begin on 1 August 2025 and will use an existing meningitis B vaccine, known as 4CMenB, to help combat soaring cases of gonorrhoea and growing concerns over antibiotic resistance.

The sexually transmitted infection (STI) reached record levels in England in 2023, with more than 85,000 cases reported — the highest number since records began in 1918. Health experts have warned that strains of the bacteria responsible for gonorrhoea, neisseria gonorrhoeae, are becoming increasingly resistant to current treatments.

The 4CMenB vaccine is currently used in the NHS childhood immunisation programme to protect against meningococcal group B disease, which can lead to serious conditions such as meningitis and sepsis. It is routinely administered to babies at eight weeks, 16 weeks, and one year of age. The vaccine contains proteins from neisseria meningitidis, a bacterium closely related to the gonorrhoeae-causing strain, and has shown moderate effectiveness against gonorrhoea in clinical studies.

Research conducted by the Joint Committee on Vaccination and Immunisation (JCVI) estimates that the 4CMenB jab could provide between 32.7% and 42% protection against gonorrhoea. While it is not expected to completely prevent infection, experts say it significantly reduces the risk and offers vital protection, particularly for groups most at risk.

Dr Amanda Doyle, national director for primary care and community services at NHS England, said: “The launch of a world-first routine vaccination for gonorrhoea is a huge step forward for sexual health. It will be crucial in protecting individuals, helping to prevent the spread of infection, and reducing the rising rates of antibiotic-resistant strains of the bacteria.”

The vaccine will be offered through local authority-commissioned sexual health services, with eligible individuals identified and contacted in the coming weeks. At their appointment, patients will also be offered vaccinations for Read More…..