Before considering Tazzle, it is crucial to review your medical history and any existing health conditions. Tazzle, like other ED treatments, can interact with certain health conditions and medications, potentially leading to complications. For individuals with heart conditions, such as coronary artery disease or recent heart attack, Tazzle may not be suitable due to potential interactions and the stress sexual activity places on the heart. Similarly, those with high or low blood pressure should exercise caution, as Tazzle can affect blood pressure levels. It is also essential to consider other medications you are taking. Tazzle can interact with nitrates (used for angina) and alpha-blockers (used for high blood pressure and prostate issues), potentially leading to severe drops in blood pressure. Always discuss your full medication list with your healthcare provider to avoid harmful interactions.