The effectiveness of Vigora 100 Mg lies in its ability to enhance the natural physiological process of achieving an erection. When a man is sexually stimulated, nitric oxide is released into the erectile tissue of the penis. This stimulates an enzyme called guanylate cyclise to produce cyclic guano sine monophosphate (camp), which relaxes the smooth muscles in the blood vessels of the penis. This relaxation allows increased blood flow, which is essential for achieving and maintaining an erection. Sildenafil Citrate in Vigora 100 Mg works by inhibiting the enzyme PDE5, which breaks down camp. By blocking PDE5, Sildenafil Citrate ensures that camp levels remain elevated, prolonging the vasodilation effect and enhancing erectile function. This mechanism of action is why Vigora 100 Mg is effective for most men with ED, enabling them to achieve reliable erections when sexually stimulated. Originally developed to treat hypertension and angina, Sildenafil Citrate was serendipitously found to have a remarkable effect on penile erections during clinical trials. Its approval for ED treatment revolutionized the management of this condition, providing a safe and effective oral medication for millions of men globally.