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NEW QUESTION 42
A protocol for a pivotal registration trial of a new product is submitted to a major regulatory authority for review and approval. The regulatory authority issues the company a written commitment that if the studies are completed as outlined in the protocol and the results meet the pre-specified criteria for efficacy and safety, the product will be approved.
During the final week of the review of the marketing application, which has fully met all pre- specified criteria, the company receives a letter from the regulatory authority stating that it no longer believes that the product will be approved based on a recent withdrawal of a similar product in another country.
What is the BEST response?

A. Review the regulatory guidelines to determine how to proceed.B. Consult with the legal department to discuss the best course of action.C. Notify the regulatory authority regarding Its obligation to honor the commitment to approve the application.D. Request a meeting with the regulatory authority to discuss the application.

Answer: D

 

NEW QUESTION 43
Which of the following is the MOST desirable timing and approach for a regulatory affairs professional who wants to provide feedback on proposed new regulations?

A. After the enactment of the regulation, through a product-specific meetingB. After the enactment of the regulation, through the industry representativeC. Before the enactment of the regulation, through the industry representativeD. Before the enactment of the regulation, through formal comments gathering process

Answer: D

 

NEW QUESTION 44
During several monitoring visits, a clinical trial monitor identifies serious and repeated noncompliance on the part of the PI. What action should the sponsor take?

A. Terminate the PI and inform the regulatory authorities.B. Inform the institution that granted a medical license to the Pi.C. Send a letter of complaint to the Ethics Committee that approved the site.D. Increase the frequency of monitoring visits.

Answer: A

 

NEW QUESTION 45
Company X has a patent for an anti-inflammatory drug that will expire in one year. In order to minimize the effect of the patent expiration, which is the BEST action for the company to take?

A. Develop a generic version of the drug.B. Explore litigation strategy for patent infringements on the drug.C. Develop a better brand-name drug in the same class.D. Conduct a Phase III study for a new unrelated indication of the drug.

Answer: A

 

NEW QUESTION 46
The regulatory authority contacts the regulatory affairs professional regarding a complaint about a drug produced by the company. A consumer reported to the regulatory authority that the tablets have a slightly different color and break easily.
Which of the following actions should the regulatory affairs professional take?

A. Respond to the regulatory authority that the product subject to the complaint is most likely a counterfeit product.B. Respond to the regulatory authority that the company will provide copies of the relevant
QC records for batch release.C. Ask that the regulatory authority provide the actual product subject to the complaint.D. Ask that the regulatory authority provide the batch number printed on the packaging of the affected product.

Answer: D

 

NEW QUESTION 47
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