The selection of the appropriate buffer for a biopharmaceutical manufacturing process is critical. Buffers must be selected based on their pH range, buffering capacity, and compatibility with other components of the process. The choice of Biopharma Buffer can also impact the stability and solubility of the protein of interest. There are several types of buffers that are commonly used in biopharmaceutical manufacturing processes. These include phosphate buffers, Tris buffers, histidine buffers, and acetate buffers.

Each type of Biopharma Buffer has specific advantages and disadvantages and must be carefully evaluated to determine its suitability for a particular process. In addition to the selection of the appropriate buffer, the concentration of the buffer must also be carefully controlled. Buffers must be added in the correct concentration to achieve the desired pH and buffering capacity. If the concentration is too low, the pH may not be stable, and if the concentration is too high, it can impact the solubility and stability of the protein.