The process of removing germs from a fluid stream without adversely affecting the final product is known as Sterile Filtering. Numerous pharmaceutical and medical items are subjected to bioburden testing as a quality control measure. If a sterile filtered bulk solution is not infused into the final product containers within 24 hours, the sterile filtration should, unless otherwise justified, be done again right away. Prior to any additional bioburden minimization step after the holding period, additional bioburden testing must be completed.

 

The holding period needs to be adequately supported. The process of eliminating microorganisms from a fluid stream without harming the end result is known as sterilising filtration. Patients' safety, patient risk reduction, and the creation of more useful goods with benign side effects are the goals of Sterile Filtering. filtering tools and filters are used in sterile filtering. These are available in sealed packaging and can be pre-sterilized for initial sterilisation.

 

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